7rsi

The cryo-EM map of KIF18A bound to KIFBP

spinqualitylabelsall models 7rsi, resolution 4.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7rsi is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.9Å Ligands: ADP, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease KBP_HUMAN Goldberg-Shprintzen megacolon syndrome. The disease is caused by variants affecting the gene represented in this entry. Function KBP_HUMAN Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. Publication Abstract from PubMed [Figure: see text]. Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.,Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MA Sci Adv. 2021 Nov 19;7(47):eabj9812. doi: 10.1126/sciadv.abj9812. Epub 2021 Nov, 19. PMID:34797717 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Kinesin 3D Structures

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