7rtk
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Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution
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Structural highlights
DiseaseNFS1_HUMAN Severe neonatal lactic acidosis due to NFS1-ISD11 complex deficiency. FunctionNFS1_HUMAN Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.[1] See AlsoReferences
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This page was last modified 16:38, 18 October 2023.