7ss7
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Crystal structure of Klebsiella LpxH in complex with JH-LPH-50
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Structural highlights
FunctionA0A1S0WIC1_KLEPN Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575][SAAS:SAAS00911811] Contents | ||||||||||||||||||||
This page was last modified 09:39, 25 October 2023.