7t7s

R-27 in Complex with S. aureus DHFR and tricyclic-NADPH (tNADPH)

spinqualitylabelsall models 7t7s, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7t7s is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: 06U, ACT, XNP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DYR_STAAU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

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