7v8t
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Crystal structure of class II pyruvate aldolase from Pseudomonas aeruginosa.
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Structural highlights
FunctionHPAAL_PSEAI Aldolase which can catalyze in vitro the aldolisation reaction between hydroxypyruvate (HPA) or pyruvate (PA) and D-glyceraldehyde (D-GA) (Ref.1). The condensation of hydroxypyruvate and D-glyceraldehyde produces (3R,4S,5R)-3,4,5,6-tetrahydroxy-2-oxohexanoate as the major product, 2-dehydro-D-gluconate and 2-dehydro-D-galactonate (Ref.1). The condensation of pyruvate and D-glyceraldehyde produces 2-dehydro-3-deoxy-L-galactonate as the major product and 2-dehydro-3-deoxy-D-gluconate (Ref.1). Also catalyzes the retro-aldol type decarboxylation of oxaloacetate, a general property of known pyruvate aldolases (Ref.1).[UniProtKB:Q47098] See AlsoContents | ||||||||||||||||||||
This page was last modified 11:44, 30 October 2024.