7vkr

Crystal structure of D. melanogaster SAMTOR in complex with SAM

spinqualitylabelsall models 7vkr, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7vkr is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CIT, MSE, SAM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [SAMTR_DROME] S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling (PubMed:29123071). Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1 (PubMed:29123071). Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.[HAMAP-Rule:MF_03044]

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