7wi8

Cryo-EM structure of inactive mGlu3 bound to LY341495

spinqualitylabelsall models 7wi8, resolution 4.17Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7wi8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: NAG, Z99 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [GRM3_HUMAN] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

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