7x4f

Native CD-NTase LpCdnE

spinqualitylabelsall models 7x4f, resolution 2.46Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7x4f is a 1 chain structure with sequence from Legionella pneumophila. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.46Å Ligands: SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CDNE2_LEGPN CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection (Probable). A type I-B(UU) CBASS system (PubMed:32839535). Cyclic dinucleotide synthase that catalyzes the synthesis of 3',3'-cyclic UMP-UMP (c-di-UMP) as the major product, and of 3',3'-cyclic CMP-UMP as a minor product, that are second messengers for cell signal transduction.

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