7xxh

Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11

spinqualitylabelsall models 7xxh, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7xxh is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.9Å Ligands: 6AD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function P2RY1_HUMAN Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

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