7yz7
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Crystal structure of the zebrafish FoxH1 bound to the TGTGGATT site
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Structural highlights
FunctionFOXH1_DANRE Transcriptional activator. Activates an activin response element (ARE). Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Modulator of nodal signaling required for organizer formation. Also required for the development of dorsal axial structures and left-right symmetry.[1] [2] See AlsoReferences
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This page was last modified 13:27, 1 February 2024.