8b4l

Crystal structure of a selenomethionine-labeled hydropyrene synthase (M75L variant) in its closed conformation

spinqualitylabelsall models 8b4l, resolution 3.39Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8b4l is a 6 chain structure with sequence from Streptomyces clavuligerus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.394Å Ligands: AHD, MG, MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HPS_STRCL Terpene synthase that catalyzes the conversion of geranylgeranyl diphosphate (GGPP) into a mixture of diterpenes, including hydropyrene (HP), hydropyrenol (HPol), isoelisabethatriene and traces of isoelisabethatriene B (PubMed:25605043, PubMed:28696553, PubMed:35965858). Hydropyrene is the main product (PubMed:25605043, PubMed:28696553). Some other diterpenoids are also produced in very low quantities (PubMed:25605043).

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