Structural highlights
Function
LP9C_EMENI Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 oxidation products (PubMed:27075737, PubMed:35658600). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:35658600).[1] [2]
References
- ↑ Jagadeeswaran G, Gainey L, Prade R, Mort AJ. A family of AA9 lytic polysaccharide monooxygenases in Aspergillus nidulans is differentially regulated by multiple substrates and at least one is active on cellulose and xyloglucan. Appl Microbiol Biotechnol. 2016 May;100(10):4535-47. PMID:27075737 doi:10.1007/s00253-016-7505-9
- ↑ Terrasan CRF, Rubio MV, Gerhardt JA, Cairo JPF, Contesini FJ, Zubieta MP, Figueiredo FL, Valadares FL, Corrêa TLR, Murakami MT, Franco TT, Davies GJ, Walton PH, Damasio A. Deletion of AA9 Lytic Polysaccharide Monooxygenases Impacts A. nidulans Secretome and Growth on Lignocellulose. Microbiol Spectr. 2022 Jun 29;10(3):e0212521. PMID:35658600 doi:10.1128/spectrum.02125-21
