8bv8

Crystal structure of the phage Mu protein Mom inactive mutant S124A

spinqualitylabelsall models 8bv8, resolution 2.03Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8bv8 is a 2 chain structure with sequence from Escherichia phage Mu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.03Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MOM_BPMU Iron-binding protein that performs methylcarbamoylation of adenine using acetyl CoA (PubMed:32369169). This chemical modificaltion makes the viral DNA resistant to a variety of host type I and type II restriction enzymes by modifying approximately 15% of DNA adenine residues (PubMed:32369169). The modification called momylation changes adenine for N6-methylcarbamoyl adenine and occurs just before packaging (PubMed:1258376, PubMed:32369169). Target sequences are 5'-(C or G)-A-(Cor G)-N-(C or T)-3' (PubMed:1258376). Also usually modifies adenine residues in the host cellular DNA (PubMed:1258376).

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