8cyo

Nurr1 Covalently Bound to a Synthetic Ligand, 10.25, via a Disulfide Bond

spinqualitylabelsall models 8cyo, resolution 2.41Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8cyo is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.41Å Ligands: CL, OBJ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NR4A2_HUMAN Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).

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