8d1i

hBest1 1uM Ca2+ (Ca2+-bound) closed state

spinqualitylabelsall models 8d1i, resolution 1.82Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8d1i is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 1.82Å Ligands: CA, MC3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease BEST1_HUMAN Nanophthalmos;Adult-onset foveomacular vitelliform dystrophy;Best vitelliform macular dystrophy;MRCS syndrome;Autosomal recessive bestrophinopathy;Autosomal dominant vitreoretinochoroidopathy;Retinitis pigmentosa. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function BEST1_HUMAN Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. See Also Bestrophin 3D structures

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