8d1k

hBest1 Ca2+-bound partially open neck state

spinqualitylabelsall models 8d1k, resolution 2.28Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8d1k is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.28Å Ligands: CA, MC3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease BEST1_HUMAN Nanophthalmos;Adult-onset foveomacular vitelliform dystrophy;Best vitelliform macular dystrophy;MRCS syndrome;Autosomal recessive bestrophinopathy;Autosomal dominant vitreoretinochoroidopathy;Retinitis pigmentosa. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function BEST1_HUMAN Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. See Also Bestrophin 3D structures

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