8fwl

Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone

spinqualitylabelsall models 8fwl, resolution 2.19Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8fwl is a 1 chain structure with sequence from Lyssavirus australis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.19Å Ligands: PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q9YZ24_9RHAB A0A7M4C440_9RHAB Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.[RuleBase:RU004918] See Also Nucleoprotein 3D structures

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