8ght

Cryo-electron microscopy structure of the zinc transporter from Bordetella bronchiseptica

spinqualitylabelsall models 8ght, resolution 3.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ght is a 2 chain structure with sequence from Bordetella bronchiseptica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.05Å Ligands: CD, PTY Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ZIP_BORBR Selective electrodiffusional channel that mediates the uptake of Zn(2+). Exploits in vivo zinc concentration gradients (maintained by cellular zinc homeostasis) to passively move zinc ions into the cytoplasm. ZIPB-mediated zinc flux is dependent upon pH, but independent of the proton motive force. Is also able to import Cd(2+), but is not permeable to Co(2+), Cu(2+), Fe(2+), Mn(2+) and Ni(2+).

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