8gvz

Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil

spinqualitylabelsall models 8gvz, resolution 1.97Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8gvz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.97Å Ligands: KCX, URF, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PYR1_HUMAN This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

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