8hvj

The structure of the E. coli mRNA endoonuclease YiCC

spinqualitylabelsall models 8hvj, resolution 4.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8hvj is a 3 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 4.05Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function YICC_ECOLI Contributes to degradation of small RNA (sRNA) RhyB. Upon overexpression suppresses sRNA-mediated RhyB-silencing of multiple RNA targets but not other sRNA's targets; overexpression leads to loss of RhyB sRNA. Enables degradation of RhyB by 3' to 5' exoribonuclease PNPase (pnp) (PubMed:34210798). Endonucleolytically cleaves ssRNA, probably generating a 3'-OH and a 5'-phosphate group (PubMed:34815358).

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