8i40

Crystal structure of ASCT from Trypanosoma brucei in complex with CoA.

spinqualitylabelsall models 8i40, resolution 2.79Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8i40 is a 4 chain structure with sequence from Trypanosoma brucei brucei TREU927. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.79Å Ligands: ACT, CA, COA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q386P1_TRYB2 Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.[PIRNR:PIRNR000858]

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