Structural highlights
8iog is a 20 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 2.88Å |
| Ligands: | CDL, FES, HEC, HEM, PEE |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
CYB_PIG Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.[1]
References
- ↑ Hao GF, Wang F, Li H, Zhu XL, Yang WC, Huang LS, Wu JW, Berry EA, Yang GF. Computational Discovery of Picomolar Q(o) Site Inhibitors of Cytochrome bc(1) Complex. J Am Chem Soc. 2012 Jun 27. PMID:22690928 doi:10.1021/ja3001908
