8ius

Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase with reduced Cys86

spinqualitylabelsall models 8ius, resolution 2.14Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ius is a 2 chain structure with sequence from Streptomyces lavendulae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.14Å Ligands: MG, MN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DCSB_STRLA Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent. Catalyzes the hydrolysis of N(omega)-hydroxy-L-arginine (NHA) to yield hydroxyurea (HU) and L-ornithine.

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