8izs

Structure of a triple-helix region of human collagen type XVII

spinqualitylabelsall models 8izs, resolution 1.53Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8izs is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.53Å Ligands: ACE, HYP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease COHA1_HUMAN Late-onset junctional epidermolysis bullosa;Intermediate generalized junctional epidermolysis bullosa;Epithelial recurrent erosion dystrophy;Localized junctional epidermolysis bullosa. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function COHA1_HUMAN May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.

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