8j4y
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Structure of Mycobacterium tuberculosis NrdF2:NrdIcomplex (reduced) determined at 3 angstrom resolution
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Structural highlights
FunctionRIR2B_MYCTU Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Two genes for this protein are present in M.tuberculosis; this is the active form. When coexpressed in E.coli with nrdE the 2 proteins complement a temperature-sensitive E.coli mutant.[1] References
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This page was last modified 07:00, 9 October 2024.