8jfl

PhK holoenzyme in active state, muscle isoform

spinqualitylabelsall models 8jfl, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8jfl is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.9Å Ligands: ADP, FAR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease KPB1_HUMAN Glycogen storage disease due to muscle phosphorylase kinase deficiency. The disease is caused by variants affecting the gene represented in this entry. Function KPB1_HUMAN Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

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