8jxl

Human 3-methylcrotonyl-CoA carboxylase in MCCU state with MCoA

spinqualitylabelsall models 8jxl, resolution 2.98Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8jxl is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.98Å Ligands: BTI, TW3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease MCCB_HUMAN 3-methylcrotonyl-CoA carboxylase deficiency. The disease is caused by variants affecting the gene represented in this entry. Function MCCB_HUMAN Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.

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