Structural highlights
8kig is a 2 chain structure with sequence from Escherichia coli, Homo sapiens, Pyrococcus abyssi GE5 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 3.1Å |
| Ligands: | 4J2, ACE, CA, NH2, NLE |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
MC3R_HUMAN Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.[UniProtKB:P33033]C562_ECOLX Electron-transport protein of unknown function.Q9V2J8_PYRAB
