8orj
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Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1.
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Structural highlights
FunctionRTCB_HUMAN Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.[HAMAP-Rule:MF_03144][1] [2] References
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This page was last modified 06:11, 30 October 2024.