8ov6

Ternary structure of bivalent glue degrader compound 1 bound to BRD4 and DCAF16:DDB1deltaBPB

spinqualitylabelsall models 8ov6, resolution 3.77Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ov6 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.77Å Ligands: U79, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DCA16_HUMAN Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins.

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