8ps0
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Cryo-EM structure of Sodium proton exchanger NhaA with bound cardiolipin
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Structural highlights
FunctionNHAA_ECOLI Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.[1] References | ||||||||||||||||||||
This page was last modified 10:56, 3 September 2025.