8q6o
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X. laevis CMG dimer bound to dimeric DONSON - without ATPase
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Structural highlights
FunctionPSF1_XENLA Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.[1] References
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This page was last modified 14:11, 18 October 2023.