8qmo

Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex

spinqualitylabelsall models 8qmo, resolution 2.76Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8qmo is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.76Å Ligands: ADP, MG, MOO, W62 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HS90B_HUMAN Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Proteopedia Page Contributors and Editors (what is this?)

OCA