8qn5

M. tuberculosis salicylate synthase MbtI in complex with methyl-AMT (new crystal form)

spinqualitylabelsall models 8qn5, resolution 1.54Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8qn5 is a 4 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.544Å Ligands: 0GA, FLC, GOL, NH4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MBTI_MYCTU Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.

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