8r66

Crystal structure of ThsA Macro domain in complex with signaling molecule

spinqualitylabelsall models 8r66, resolution 2.23Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8r66 is a 2 chain structure with sequence from Bacillus amyloliquefaciens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.23Å Ligands: SO4, Y65 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function THSA_BACAY Probable membrane protein component of the Thoeris antiviral defense system, composed of ThsA and ThsB. Expression of ThsA and ThsB in B.subtilis (strain BEST7003) confers resistance to phages SBSphiC, SBSphiJ and SPO1 (PubMed:29371424). Activation by a signal generated by ThsB leads to phage resistance (By similarity).[UniProtKB:J8G6Z1]

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