8rd3
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Crystal structure of Saccharomyces cerevisiae Nmd4 protein bound to Upf1 helicase domain
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Structural highlights
FunctionRENT1_YEAST RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs (PubMed:30218034, PubMed:8896465). Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA (PubMed:30218034).[1] [2] References
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This page was last modified 08:17, 14 August 2024.