8rev

Structure of XPD stalled at a Y-fork DNA containing a interstrand crosslink

spinqualitylabelsall models 8rev, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8rev is a 4 chain structure with sequence from Chaetomium thermophilum and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.1Å Ligands: ADP, L5R, SF4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function G0RZH0_CHATD ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.[ARBA:ARBA00025396]

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