8rhn

Structure of the 55LCC ATPase complex

spinqualitylabelsall models 8rhn, resolution 4.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8rhn is a 16 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease AFG2A_HUMAN Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome. The disease is caused by variants affecting the gene represented in this entry. Function AFG2A_HUMAN ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024). Acts together with AFG2B, AIRIM and CINP (PubMed:35354024). May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity).[UniProtKB:Q3UMC0]

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