8rsm

Crystal structure of Streptococcus pyogenes macrodomain in complex with ADP-ribose

spinqualitylabelsall models 8rsm, resolution 1.87Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8rsm is a 1 chain structure with sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.87Å Ligands: AR6, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ADPRH_STRP1 ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (By similarity). Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L, by releasing ADP-ribose from the target protein. May be involved in the modulation of the response to host-derived oxidative stress.[UniProtKB:P0DN70]

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