8ry4 | pdb_00008ry4
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CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation II.
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Structural highlights
FunctionGUAB1_MYCS2 Involved in the purine-salvage pathway (PubMed:35338694). Catalyzes the NADPH-dependent conversion of GMP to IMP (PubMed:35338694). Is not essential for viability, but may contribute to the regulation of the purine nucleotide pool by recycling GMP to IMP (PubMed:35338694).[1] References
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This page was last modified 06:06, 20 August 2025.