8sgl
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CCT G beta 5 complex closed state 15
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Structural highlights
DiseaseTCPE_HUMAN Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. FunctionTCPE_HUMAN Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.[1] See AlsoReferences
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This page was last modified 09:08, 4 June 2025.