8snp
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Crystal structure of mouse Netrin-1 in complex with samarium ions
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Structural highlights
FunctionNET1_MOUSE Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis (By similarity). Contents | ||||||||||||||||||||
This page was last modified 12:31, 23 October 2024.