8sxn

Structure of NLRP3 and NEK7 complex

spinqualitylabelsall models 8sxn, resolution 4.04Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8sxn is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.04Å Ligands: 7YN, ATP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NEK7_HUMAN Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1.

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