8t1l
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Atomic model of the mammalian mouse Mediator complex with CKM module
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Structural highlights
FunctionMED7_MOUSE Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Contents | ||||||||||||||||||
This page was last modified 07:19, 3 July 2024.