8tqz

Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit

spinqualitylabelsall models 8tqz, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8tqz is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.9Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease EI2BA_HUMAN Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry. Function EI2BA_HUMAN Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

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