8trj

Cryo-EM structure of the rat P2X7 receptor in complex with the high-affinity agonist BzATP

spinqualitylabelsall models 8trj, resolution 2.78Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8trj is a 3 chain structure with sequence from Rattus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.78Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function P2RX7_RAT Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

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