8tsk

Structure of human LIAS in the presence of 5'-deoxyadenosine and octanoyl-modified peptide

spinqualitylabelsall models 8tsk, resolution 1.58Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8tsk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.58Å Ligands: 5AD, LYS, MET, OCA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease LIAS_HUMAN Lipoic acid synthetase deficiency. The disease is caused by variants affecting the gene represented in this entry. Function LIAS_HUMAN Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.[HAMAP-Rule:MF_03123]

Proteopedia Page Contributors and Editors (what is this?)

OCA