8u0b
From Proteopedia
Jump to navigationJump to search
Crystal structure of Lyssavirus rabies (Nishigahara strain) nucleoprotein in complex with phosphomimetic phosphoprotein S48E
| ||||||||||||
Structural highlights
FunctionB9VMI2_9RHAB Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.[RuleBase:RU004918]Q5NU29_9RHAB Contents | ||||||||||||||||||
This page was last modified 05:15, 23 April 2025.