8ud9

Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304

spinqualitylabelsall models 8ud9, resolution 2.04Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ud9 is a 20 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.04Å Ligands: YRE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PSA6_HUMAN The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

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