8uh0

SOS2 co-crystal structure with fragment bound (compound 10)

spinqualitylabelsall models 8uh0, resolution 2.73Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8uh0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.73Å Ligands: WRN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SOS2_HUMAN Noonan syndrome. The disease is caused by mutations affecting the gene represented in this entry. Function SOS2_HUMAN Promotes the exchange of Ras-bound GDP by GTP.[UniProtKB:Q62245]

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